After quitting university and becoming a freelancer in September last year, my life has changed quite a bit. The most irritating thing is the amount of non-productive time I have to spend to be able to do productive work. While I was in university, almost 90% of the time I was in the office was spent doing actual work (not necessarily for the thesis or the faculty, but you know ;-)) -- nowadays I find myself organizing things, doing phone calls, traveling, processing e-mail and snail-mail, etc. for nearly 50% of the time.
It's either me being not well prepared for this kind of work or things really got more complicated. I guess I have to hire some kind of assistant to help me spending more time doing actual development and lowering all this organization overhead.